I've been selling eyeglasses frames via the web for 3 years. I am not US based, but have found that it is almost as if the rest of the English speaking world doesn't exist - the US market is so huge - 90% of our enquiry and sales comes from the US.
So in answer to your question - price it in US$ - the rest of the world doesn't matter.
Cahaba Heights Eyeglasses
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